After over a decade of research at Queen Mary University of London, we discovered a natural combination of nutrients that supports fullness, naturally.
Resulting in increased food noise and difficulty controlling appetite and weight.
Chronic cortisol dampens L-cell responsiveness.
Decreases the guts ability to "taste nutrients" and activate hormone production optimally
Disrupts circadian release of gut hormones.
Background inflammation blunts gut signalling.
Each oil was chosen for a specific fatty acid that L-cells respond to. Together, they help you improve gut-brain signalling and improve your gut health.
A medium-chain triglyceride containing capric acid — a short-chain fatty acid that supports the gut functions that help manage hunger.
A medium-chain fatty acid that supports gut hormone and microbial balance — strengthening fullness cues from the inside.
An omega-3 the gut directly senses — prompting L-cells to secrete GLP-1 and PYY to tell your brain it's full.
Your gut and your brain are in constant conversation.
When it comes to fullness, two of the key gut hormones are PYY and GLP-1. Together, they help your brain recognise and respond to what you've eaten
Released by L-cells in the lower gut in response to food. Slows gastric emptying, reduces hunger and extends satisfaction between meals.
Co-released with PYY from the same L-cells. Slows gut transit, supports blood-sugar regulation and amplifies the "I'm full" signal to the brain.
Elcella's nutrient formulation is precisely engineered — three natural oils, chosen for their fatty acid composition — proven to activate receptors on L-cells and trigger natural GLP-1 and PYY release.(Peiris et al., Gut, 2022.)
A pH-sensitive shell protects three precisely-blended natural oils from the stomach and small intestine.
Oils are delivered to the ileum and colon — the part of the gut with the highest concentration of L-cells.
Capric, lauric and alpha-linolenic acids bind to receptors on L-cells, stimulating natural hormone release.
PYY and GLP-1 travel to the brain — reduced food noise, steadier appetite, easier weight management.
Elcella is the result of 15 years of work led by gut neuroscientists Dr Madusha Peiris and Dr Ruby Aktar.
We discovered that the gut can taste nutrients — from the stomach all the way down to the rectum. The lower gut isn't a passive tube; it's a sensing organ.
Attention turned to L-cells — Elcella's namesake — and how they release GLP-1 and PYY hormones when they taste specific nutrients (Peiris et al., Gut 2015).
We discovered L-cells respond especially strongly to two specific fatty acid types — laying the foundation for the Elcella formula.
Two clinical trials confirmed the formula boosted GLP-1 and PYY hormone release, reducing food intake by 18% in a single meal (Peiris et al., Gut, 2022).
An additional clinical study showed appetite responses are dose-dependent — allowing us to fine-tune the Elcella protocol.
After more than a decade of research, Elcella is here — a science-backed formula to help support your body's natural systems to control appetite.
Elcella is a long-term, biology-led protocol — three phases that move with you as your gut relearns how to understand its own signals.
Suboptimal diets, shifting cravings and daily stress produce inconsistent hunger signals and loud food noise — constant thoughts about the next meal, snacking on autopilot, struggling with cravings.
The maximum dose for maximum impact. Your gut relearns how to recognise appetite signals and communicate them to the brain. Little by little, food takes up less mental space — smaller portions, fewer snacks, quieter cravings.
You're making intuitive eating decisions, naturally sensing fullness and hunger. You may notice a shift in weight, higher energy levels, and healthier choices that feel easier than effortful.
Your gut signals fullness to the brain naturally — Elcella is light support, not the engine. Food no longer occupies your every thought; eating returns to its rightful place in the background of your life.
Think of GLP-1 and PYY as your body's built-in appetite guide. They help you recognise when you've had enough food, and when you need more.
Modern life — poor diets, poor sleep, stress — can disrupt the release of these hormones, making appetite feel unpredictable and food noise loud.
By supporting gut function, Elcella helps your gut–brain connection, encouraging your body to understand its appetite cues and prevent overeating.
Elcella is a natural, science-backed formula that nourishes the gut to restore its ability to signal appetite cues to the brain. Elcella delivers targeted nutrition that empowers the gut to kick into "appetite-reducing" mode.
While GLP-1 medications mimic this action pharmacologically, Elcella does it naturally — working with the body to help it self-regulate, leading to long-term, sustainable results.
The three main ingredients in Elcella (coconut oil, MCT oil and linseed oil) can be eaten in a normal diet — but they're usually broken down in the stomach and absorbed in the small intestine, meaning very little reaches the lower gut.
Elcella delivers a precise dose directly to the lower gut, where there's a high concentration of L-cells. By delivering these nutrients to the right place, in the right amount, Elcella supports a stronger, natural release of satiety hormones — something difficult to achieve through diet alone.
Elcella is designed as a long-term, biology-led approach, with the first three months focused on building the foundation for change. This initial period allows your body time to adjust and for gut-brain signalling to become more consistent.
After three months, many people choose to continue to build on their results; others reduce their dose. Every gut is different, and not everyone's starting point and journey will be the same.
Elcella is designed for adults looking to support healthy appetite regulation, improve satiety and develop more balanced eating habits — sustainable weight management, not rapid weight loss.
In our 12-week consumer trial, 94% of participants noticed improved appetite control and reduced food noise, 70% noticed reduced hunger between meals, and participants lost an average of 6kg.*
Elcella is designed to work naturally with your body. But if you're taking any medications or other supplements, we recommend speaking with your healthcare provider first.
Of course — citations available on request, or via hello@elcella.com. Key references include Peiris et al., Gut, 2022.
A science-backed, natural protocol for reconnecting with your appetite — built to last years, not weeks.
